One of the most common things patients say in consultation is:

“I eat well, I exercise, but this one area just won’t change.”

And in many cases, they’re absolutely right. Some fat deposits are biologically resistant to weight loss.

Fat Cells Don’t All Behave the Same

The human body stores fat in specialized cells called adipocytes. But these cells differ depending on their location. Certain areas—such as the:

• lower abdomen
• flanks
• inner thighs
• under the chin

contain fat that is metabolically more resistant to breakdown. This means even when you lose weight, those areas may change very little.

Genetics Plays a Major Role

Your body shape is largely determined by genetics. Some people naturally store fat in the:

• abdomen
• hips
• thighs
• arms

Even with significant weight loss, these patterns tend to persist. This is why two people can lose the same amount of weight but look very different in body shape.

Hormones Also Influence Fat Distribution

Hormonal changes can significantly affect where fat accumulates.

Examples include:

Menopause

Lower estrogen levels can lead to increased abdominal fat storage.

Pregnancy

Hormonal shifts and tissue changes may alter fat distribution.

Weight loss medications such as GLP-1 drugs

Rapid weight loss can change body composition in ways that reveal persistent fat pockets or loose skin.

This Is Where Body Contouring Comes In

Procedures such as liposuction are designed to address fat that does not respond to lifestyle changes. These procedures are not substitutes for healthy habits. Instead, they help refine areas that remain resistant despite them. When used appropriately, body contouring can create a more balanced and proportional silhouette.

Schedule your consultation with Dr DiFrancesco to hear more about your options

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