Thigh lift surgery is widely considered one of the most demanding procedures in body contouring. The inner thigh is constantly exposed to gravity, tension, and moisture, and all three work against healing. At DiFrancesco Plastic Surgery, Dr. DiFrancesco sees the future of the thigh lift as one that makes this challenging area far more forgiving. […]

NAD+ is not a peptide. It is a coenzyme, not a chain of amino acids, but a small organic molecule called nicotinamide adenine dinucleotide that is found in every living cell in the human body. Technically, NAD+ does not belong in a discussion built around peptide therapy. DiFrancesco Plastic Surgery covers it anyway, and here […]

The first two volumes of this peptide and longevity medicine series followed a clear structure. Volume One built the foundation: growth hormone, fat metabolism, tissue repair, immune function, and skin remodeling, six compounds addressing six distinct physiological systems within integrated aesthetic and longevity medicine. Volume Two went further into emerging research: completing the growth hormone […]

Every peptide in this eleven-post series has been derived from somewhere: the pituitary, the stomach, the thymus, the pineal gland, growth hormone itself. MOTS-C is derived from none of those places. MOTS-C is encoded in mitochondrial DNA. That single fact makes it one of the most conceptually novel compounds in this entire series, and one […]

DiFrancesco Plastic Surgery offers physician-led regenerative treatments for aging, weight loss changes, hormone imbalance, hair loss, and skin rejuvenation through biologically-based aesthetic medicine. What Is Regenerative Aesthetics? The aesthetic medicine industry is experiencing a fundamental transformation. After decades of traditional fillers and neurotoxins, patients and physicians are now asking a different question: How can we […]

Patients often hear several terms used interchangeably: micro-liposuction, mini liposuction, awake liposuction, and traditional liposuction. While they all involve removing fat, the scale, technique, and goals of these procedures are quite different. Understanding those differences is critical when choosing the right treatment. What Is Micro-Liposuction? Micro-liposuction focuses on removing small, localized fat deposits using extremely small cannulas. It is often […]

If you’ve recently invested in yourself through plastic surgery, you’re likely focused on the finish line: the big reveal. But between the operating table and the “after” photo lies the recovery phase—a period often defined by swelling, bruising, and a test of your patience. Enter Red Light Therapy (RLT), also known as Photobiomodulation. Once a niche biohacking […]